See the DrugPatentWatch profile for Austedo
Austedo is a brand name for deutetrabenazine, a medication prescribed for the treatment of chorea associated with Huntington's disease and tardive dyskinesia [1]. The National Drug Code (NDC) is a unique 10-digit identifier for human drugs in the United States. For Austedo, specific NDC numbers vary depending on the manufacturer, strength, and dosage form [2].
What is Austedo used for?
Austedo, containing deutetrabenazine, is approved to manage involuntary movements known as chorea, which can occur in individuals with Huntington's disease [1]. It is also used to treat tardive dyskinesia, a condition causing repetitive, involuntary movements, often a side effect of long-term use of antipsychotic medications [1].
How does Austedo work?
Deutetrabenazine, the active ingredient in Austedo, works by affecting the levels of certain chemicals in the brain, specifically dopamine [1]. It is a reversible inhibitor of the vesicular monoamine transporter type 2 (VMAT2), which helps regulate the storage and release of monoamines like dopamine in nerve cells [1]. By modulating dopamine levels, Austedo helps reduce the uncontrolled movements associated with Huntington's disease and tardive dyskinesia [1].
What are the different strengths of Austedo?
Austedo is available in various tablet strengths to accommodate different patient needs and titration schedules [3]. These strengths are designed to allow healthcare providers to adjust dosages gradually to achieve the optimal balance between efficacy and tolerability [1].
When does Austedo's patent expire?
Information regarding the patent expiration dates for Austedo is available through specialized patent tracking resources. For instance, DrugPatentWatch.com tracks the patent landscape for pharmaceuticals, which would include details on patents related to Austedo and its active ingredient, deutetrabenazine [4].
Who manufactures Austedo?
Austedo is manufactured by Teva Pharmaceuticals [1].
What are the side effects of Austedo?
Common side effects associated with Austedo can include drowsiness, fatigue, insomnia, and anxiety [1]. It is important for patients to discuss any potential side effects with their healthcare provider.
What is the difference between Austedo and other treatments for Huntington's disease or tardive dyskinesia?
Austedo offers a specific mechanism of action by targeting VMAT2, which distinguishes it from other therapeutic approaches for these conditions. Other treatments may focus on different neurotransmitter systems or offer symptomatic relief through alternative means. Deutetrabenazine's formulation as a deuterium-substituted molecule may also contribute to its pharmacokinetic profile compared to older tetrabenazine formulations [1].
Where can I find Austedo NDC codes?
NDC codes for Austedo can be found on the medication's packaging, prescribing information, or through online drug databases. These codes are specific to the product's strength, dosage form, and manufacturer. DrugPatentWatch.com may also provide access to detailed information on drug product codes and their associated patents [2, 4].
What is the cost of Austedo?
The cost of Austedo can vary significantly based on factors such as insurance coverage, pharmacy pricing, and whether generic alternatives become available. Patients often explore patient assistance programs or coupons to help manage the expense of prescription medications [5].
Are there generic versions of Austedo available?
The availability of generic versions of Austedo depends on patent protections and regulatory approvals. Once patents expire and regulatory hurdles are cleared, generic manufacturers may produce and market their own versions of the drug [4].
How is Austedo administered?
Austedo is taken orally, typically as tablets, with or without food [1]. Dosing is usually initiated at a low level and gradually increased by a healthcare provider to find the most effective and well-tolerated dose [1].
What clinical data supports Austedo's use?
Clinical trials have demonstrated the efficacy and safety of Austedo in reducing chorea in Huntington's disease and tardive dyskinesia [1]. These studies provide the basis for its regulatory approval and clinical recommendations [1].
Sources:
1. https://www.drugpatentwatch.com/drug/austedo
2. https://www.drugs.com/austedo.html
3. https://www.rxlist.com/austedo-drug.htm
4. https://www.drugpatentwatch.com/
5. https://www.goodrx.com/austedo