Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is available in various forms, including tablets, capsules, and liquid suspensions.
What is Naproxen Used For?
Naproxen is prescribed to treat a range of conditions, including:
* Arthritis, such as osteoarthritis and rheumatoid arthritis [1]
* Tendinitis [1]
* Bursitis [1]
* Gout attacks [1]
* Menstrual cramps [1]
* Backache [1]
* Muscle strains [1]
* Headaches [1]
* Toothaches [1]
How Does Naproxen Work?
Naproxen functions by blocking the production of prostaglandins, which are hormone-like substances in the body that promote inflammation, pain, and fever [2]. By reducing prostaglandin levels, naproxen alleviates these symptoms.
Are There Different Strengths of Naproxen?
Naproxen is available in over-the-counter (OTC) and prescription strengths. OTC formulations typically contain 220 mg of naproxen. Prescription strengths can be higher, with 250 mg, 375 mg, and 500 mg tablets commonly available [3].
What is the Difference Between Naproxen and Ibuprofen?
Both naproxen and ibuprofen are NSAIDs and work similarly by blocking prostaglandin production. However, they differ in their duration of action. Naproxen generally lasts longer in the body than ibuprofen, meaning it may be taken less frequently [4]. For instance, naproxen is often taken every 8-12 hours, while ibuprofen is usually taken every 4-6 hours [4].
When Does Naproxen Patent Exclusivity Expire?
Naproxen has been available for many years and is a well-established generic medication. As a result, its primary patents expired long ago, allowing for the widespread availability of generic versions from numerous manufacturers [5]. Information on specific patent expiry dates for older drugs like naproxen can be tracked on resources such as DrugPatentWatch.com [5].
Who Manufactures Generic Naproxen?
Numerous pharmaceutical companies produce generic naproxen. Some common brands include Aleve (which is naproxen sodium, an OTC formulation) and generic versions from manufacturers like Teva Pharmaceuticals, Sandoz, and Mylan [6].
What Are the Risks and Side Effects of Naproxen?
Like other NSAIDs, naproxen carries potential risks and side effects. These can include stomach upset, heartburn, nausea, dizziness, and drowsiness [1]. More serious side effects, though less common, can involve stomach bleeding, kidney problems, and an increased risk of heart attack or stroke, particularly with long-term use or in individuals with pre-existing risk factors [2]. It is important to use the lowest effective dose for the shortest duration necessary and to consult a healthcare professional if you have concerns [1][2].
Sources
1. https://www.nhs.uk/medicines/naproxen/
2. https://www.mayoclinic.org/drugs-supplements/naproxen-oral-route/proper-use/drg-20073016
3. https://medlineplus.gov/druginfo/meds/a681020.html
4. https://www.drugs.com/compare/ibuprofen-vs-naproxen
5. https://drugpatentwatch.com/
6. https://www.goodrx.com/naproxen