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Promethazine uses?

See the DrugPatentWatch profile for Promethazine

Promethazine is a first‑generation antihistamine with sedative and antiemetic effects. Common uses include:

- Allergy symptoms: relief of runny nose, sneezing, itching, watery eyes; hives and other allergic rashes
- Nausea and vomiting: prevention/tollowing in postoperative nausea, motion sickness, and drug‑induced nausea
- Sedation: short-term sleep aid or pre‑procedure sedation
- Cough suppression: in combination products (eg, promethazine with codeine)
- Pruritus: relief of itching from certain allergic conditions

Important safety notes:
- Not for use in children under 2 years (varies by country); use with caution in young children.
- Can cause drowsiness and anticholinergic effects (dry mouth, blurred vision, urinary retention); avoid driving or dangerous activities and alcohol.
- Caution in elderly, glaucoma, urinary retention, history of ulcers, or other sensitive conditions.
- Avoid or use only under supervision in pregnancy unless specifically advised by a clinician.
- IV administration is generally avoided or used with great caution (risk of severe tissue injury); IM injection or slow infusion is preferred when appropriate.

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