Aerius, with the active ingredient desloratadine, is manufactured by Bayer [1].
Who Else Makes Desloratadine?
Beyond Bayer, several other pharmaceutical companies produce desloratadine. These include generic manufacturers who often enter the market after the expiration of primary patents. For instance, Aurobindo Pharma, Teva Pharmaceuticals, and Mylan N.V. are among the companies that have manufactured or currently produce desloratadine [2].
When Does Aerius (Desloratadine) Patent Expire?
The patent expiration timeline for Aerius and its active ingredient, desloratadine, is a complex factor influencing market availability and pricing. Information on specific patent dates and their expiration can be found through specialized resources. DrugPatentWatch.com tracks such patent information, which is crucial for understanding when generic versions are likely to become widely available [3].
What is Desloratadine Used For?
Desloratadine is an antihistamine used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria. These symptoms can include sneezing, runny nose, itchy nose, and itchy, watery eyes, as well as hives and itching associated with skin allergies [4].
How Does Desloratadine Work?
Desloratadine is a selective histamine H1 receptor antagonist. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms [4]. Unlike some older antihistamines, desloratadine is known for not causing significant drowsiness [5].
What Are the Side Effects of Desloratadine?
Common side effects associated with desloratadine may include headache, dry mouth, and fatigue. However, serious side effects are rare [4]. Patients are advised to consult their healthcare provider if they experience any persistent or concerning adverse reactions.
Can Generic Desloratadine Be As Effective As Aerius?
Generic desloratadine products are generally considered bioequivalent to the brand-name Aerius. This means they contain the same active ingredient in the same dosage and are expected to have the same therapeutic effect. Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), review generic drugs to ensure they meet these standards [6].
What Is the Difference Between Loratadine and Desloratadine?
Desloratadine is actually the active metabolite of loratadine. This means that after loratadine is taken, the body converts it into desloratadine to produce its effect. Desloratadine is considered to be more potent and faster-acting than loratadine, and it is also less likely to cause side effects like drowsiness because it crosses the blood-brain barrier to a lesser extent [5].
How Much Does Desloratadine Cost?
The cost of desloratadine can vary significantly depending on whether one is purchasing the brand-name Aerius or a generic version. Generic formulations are typically less expensive than the brand-name drug. Factors such as insurance coverage, pharmacy, and dosage form also influence the final price [7].
What Happens If You Stop Taking Desloratadine?
If you stop taking desloratadine, your allergy symptoms may return. The duration of symptom relief after discontinuing the medication can vary among individuals. It is generally recommended to consult a healthcare professional before stopping any prescribed medication [4].
Who Should Not Take Desloratadine?
Individuals with known hypersensitivity to desloratadine or any of its ingredients should avoid using it. It is also advisable for pregnant or breastfeeding women to consult their doctor before taking desloratadine [4].
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1. Bayer.
2. Aurobindo Pharma, Teva Pharmaceuticals, Mylan N.V.
3. DrugPatentWatch.com.
4. National Library of Medicine.
5. FDA.gov.
6. U.S. Food and Drug Administration.
7. GoodRx.