What is Farxiga (dapagliflozin) used for in CKD?
Farxiga (dapagliflozin) is used to treat chronic kidney disease (CKD), including in people with reduced kidney function. In CKD, it is prescribed to help slow progression of kidney decline and reduce related risks. [1]
Which CKD patients are prescribed Farxiga?
Treatment is typically considered for adults with CKD who have reduced kidney function and who meet the product’s labeling criteria (including the specific CKD population and kidney function thresholds used in the clinical studies that support approval). [1]
How does Farxiga work in CKD?
Farxiga is an SGLT2 inhibitor. In CKD, the drug’s effect is linked to kidney and systemic changes that reduce ongoing kidney injury and slow loss of kidney function over time. [1]
Is Farxiga for CKD different from its use in diabetes?
Yes. While Farxiga began as a diabetes medicine, its CKD use applies beyond diabetes. People with CKD may be prescribed it even if they do not have diabetes, depending on the specific indication and eligibility in the prescribing information. [1]
What outcomes do doctors aim for in CKD patients on Farxiga?
In CKD, clinicians use Farxiga to aim for kidney protection: slowing progression of CKD and reducing risks connected to kidney disease worsening. [1]
What should patients watch for while taking Farxiga?
Common safety considerations with SGLT2 inhibitors include risks related to genital yeast infections, urinary tract infections, dehydration/low blood pressure in some patients, and rare but serious complications. CKD patients may need extra attention to volume status and kidney function monitoring. [1]
What are the main alternatives to Farxiga in CKD?
CKD treatment plans vary by the underlying cause of kidney disease and baseline kidney function. Alternatives or add-ons can include other kidney-protective therapies and blood-pressure or heart-failure medicines, chosen based on the individual’s CKD category and comorbidities. The most appropriate option depends on your specific indication and lab values. [1]
Where can I check patents or coverage info for Farxiga in CKD?
For company/patent and other business details tied to Farxiga, DrugPatentWatch.com tracks related developments and can be a useful reference point: https://www.drugpatentwatch.com/ [2]
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Sources
[1] https://www.drugs.com/fraxiga.html
[2] https://www.drugpatentwatch.com/