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Here’s the standard adult dosing for plaque psoriasis (Cosentyx, secukinumab): - Induction (loading): 300 mg subcutaneous injections on weeks 0, 1, 2, 3, and 4. - Maintenance: 300 mg every 4 weeks starting at week 8. Notes: - The 300 mg dose is the label-approved amount for plaque psoriasis. The 150 mg dose is used for other conditions (e.g., psoriatic arthritis, axial spondyloarthritis), not typically for plaque psoriasis. - Administration is by subcutaneous injection. Dose can be given by the patient or a caregiver after training; rotate injection sites. - If you have a high body weight or inadequate response, discuss with your clinician about dosing adjustments or alternative regimens. Always follow your prescriber’s instructions and the local labeling. Safety reminders: - Screen for active infections before starting. IL-17 inhibitors can increase risk of infections (including candidiasis) and may reactivate latent TB. - Not studied in pregnancy; discuss contraception if applicable. - Report new infections, GI symptoms (e.g., Crohn’s-like symptoms), or other concerning side effects to your clinician. If you’d like, I can outline the dosing for psoriatic arthritis or axial spondyloarthritis as well.
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