What specific sites on hmg coa reductase does lipitor bind to?

What sites on HMG-CoA reductase does Lipitor bind to?

HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, the first committed step in cholesterol synthesis. Lipitor binds directly to the active site of the enzyme, blocking substrate access.

Lipitor binds to the HMG-binding portion of the active site through hydrogen bonds and polar interactions with residues Ser565, Lys735, and Glu559.