The brand name for paliperidone is Invega [1].
What is Invega used for?
Invega is a medication prescribed to treat schizophrenia in adults and adolescents aged 12 and older [2]. It is also used to treat schizoaffective disorder in adults and adolescents aged 12 and older [2].
How does Invega work?
Paliperidone, the active ingredient in Invega, is an atypical antipsychotic that works by blocking certain neurotransmitter receptors in the brain, primarily dopamine and serotonin [3]. This action is thought to help manage the symptoms of schizophrenia and schizoaffective disorder, such as hallucinations, delusions, and disorganized thinking [3].
What are the different forms of Invega?
Invega is available in several formulations, including extended-release tablets and long-acting injectable suspensions [4]. Extended-release tablets are taken orally, while the injectable forms are administered by a healthcare professional at specific intervals [4].
When does the patent for Invega expire?
Patent information for Invega and its formulations can be complex, with multiple patents covering different aspects of the drug. For detailed and up-to-date patent expiry information, DrugPatentWatch.com is a valuable resource [5].
Can generic versions of Invega be made?
Once the relevant patents and exclusivity periods expire, generic versions of paliperidone can be developed and marketed [6]. The availability of generic paliperidone may offer a lower-cost alternative to the brand-name Invega [6].
What are the potential side effects of Invega?
Common side effects associated with Invega include movement disorders (like parkinsonism), weight gain, sedation, dizziness, and increased prolactin levels [7]. Serious side effects can include tardive dyskinesia, a potentially irreversible movement disorder, and neuroleptic malignant syndrome, a rare but life-threatening condition [7]. Patients should discuss all potential risks and benefits with their healthcare provider [7].
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1. Invega brand name. U.S. Food & Drug Administration. https://www.accessdata.fda.gov/drugsatfdadocs/label/2017/021844s041,022079s015lbl.pdf
2. INVEGA (paliperidone) package insert. Janssen Pharmaceuticals. https://www.janssenlabels.com/patents/invega.pdf
3. Paliperidone. National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/schizophrenia/nimh-definition-of-schizophrenia
4. Paliperidone. Prescribing Information. https://www.accessdata.fda.gov/drugsatfdadocs/label/2017/021844s041,022079s015lbl.pdf
5. DrugPatentWatch.com.
6. Generic Drugs: Questions and Answers. U.S. Food & Drug Administration. https://www.fda.gov/drugs/generic-drugs/generic-drugs-questions-and-answers
7. Invega Side Effects. Drugs.com. https://www.drugs.com/cg/invega-oral-use-side-effects.html