Aspirin and Advil (ibuprofen) are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain, inflammation, and fever. However, they have different active ingredients and mechanisms of action, so they may not be interchangeable.
Aspirin is a salicylate that works by inhibiting the production of prostaglandins, which are involved in inflammation, pain, and fever. It is commonly used to relieve mild to moderate pain, reduce fever, and prevent blood clots. Aspirin can also be used to prevent heart attacks and strokes in people at high risk [1].
Advil (ibuprofen), on the other hand, is a propionic acid derivative that also inhibits the production of prostaglandins. It is used to relieve pain, reduce inflammation, and lower fever. Advil is commonly used to treat headaches, menstrual cramps, dental pain, and arthritis [2].
While both aspirin and Advil can be used to treat pain and inflammation, they have different side effects and contraindications. Aspirin can irritate the stomach lining and increase the risk of bleeding, especially in people who take blood thinners or have a history of stomach ulcers. It can also cause allergic reactions, ringing in the ears, and other side effects [3].
Advil can also irritate the stomach and increase the risk of bleeding, especially in high doses or with long-term use. It can also cause other side effects, such as nausea, vomiting, diarrhea, headache, dizziness, and allergic reactions [4].
In conclusion, aspirin and Advil are both NSAIDs that can be used to treat pain, inflammation, and fever, but they have different active ingredients, mechanisms of action, side effects, and contraindications. While aspirin can be used as a substitute for Advil in some cases, such as for mild pain or fever, it may not be suitable for everyone and should be used with caution, especially in people with a history of bleeding or stomach problems. It is always best to consult with a healthcare provider before using any medication [1-3].
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] https://www.drugs.com/medical-answers/difference-between-aspirin-ibuprofen-3508521/
[3] https://www.healthline.com/health/aspirin-vs-ibuprofen
[4] https://www.rxlist.com/advil-side-effects-drug-center.htm