Artesunate is an antimalarial medication that is used to treat severe malaria. Allergic reactions to artesunate are possible, and in some cases, they can be life-threatening. According to the Mayo Clinic [3], signs of an allergic reaction to artesunate may include hives, difficulty breathing, swelling of the face, lips, tongue, or throat, and severe dizziness. If any of these symptoms occur, it is important to seek medical attention immediately.

The CDC [2] recommends that healthcare providers who administer artesunate be prepared to manage severe allergic reactions. The CDC's guidelines for the treatment of severe malaria include a section on the management of artesunate allergies. The guidelines recommend that healthcare providers have epinephrine and other emergency medications available in case of an allergic reaction.

Drug Patent Watch [1] lists the potential side effects of artesunate, including anaphylaxis, a severe and potentially life-threatening allergic reaction. The site notes that anaphylaxis is a rare side effect of artesunate, but it can occur in some patients.

In conclusion, while allergic reactions to artesunate are rare, they can be life-threatening. If you experience any symptoms of an allergic reaction after taking artesunate, seek medical attention immediately. Healthcare providers who administer artesunate should be prepared to manage severe allergic reactions, including having emergency medications available.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ARTESUNATE
[2] https://www.cdc.gov/malaria/resources/pdf/guilin_protocol_7171_022620.pdf
[3] https://www.mayoclinic.org/drugs-supplements/artesunate-intravenous-route/side-effects/drg-20489625?p=1