Vascepa is a prescription medication that contains the active ingredient icosapent ethyl, which is used to reduce triglyceride levels in adults with high triglycerides. Probiotics are live microorganisms that can provide health benefits when consumed in adequate amounts.

There is no clear evidence of any negative effects of combining Vascepa and probiotics. However, it is always important to consult with a healthcare professional before combining any medications or supplements.

According to the sources provided, Vascepa may cause some side effects such as joint pain, headache, and stomach upset. Probiotics may also cause some side effects such as gas, bloating, and diarrhea. It is possible that combining Vascepa and probiotics may increase the risk of these side effects, but there is no conclusive evidence to support this.

In conclusion, there is no clear evidence of any negative effects of combining Vascepa and probiotics. However, it is always important to consult with a healthcare professional before combining any medications or supplements.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/VASCEPA
[2] https://www.singlecare.com/blog/vascepa-side-effects/
[3] https://www.healthline.com/health/drugs/vascepa