What is the dosing schedule for shingrix?

Standard Dosing Schedule for Shingrix

Shingrix is given as a 2-dose series for adults 50 years and older to prevent herpes zoster (shingles) and its complications. Each dose is 0.5 mL intramuscularly, with the second dose administered 2 to 6 months after the first.[1][2]

Who Gets Shingrix and When

The CDC recommends Shingrix for:
- Adults 50 years and older, regardless of prior shingles or vaccination history.
- Adults 19 years and older who are or will be immunodecompromised (e.g., due to disease or therapy).[1][2]

For immunocompromised adults, the second dose can be given as early as 1-2 months after the first.[1]

What If the Schedule Is Delayed

If more than 6 months pass before the second dose, it can still be given—no need to restart the series. Administer at the next opportunity.[1][2]

Administration Details

Inject 0.5 mL into the deltoid region of the upper arm, using a sterile needle and syringe. Shake well before use; do not use if discolored or particles are present.[2]

Common Storage and Handling

Store refrigerated at 36°F to 46°F (2°C to 8°C). Once reconstituted, use within 6 hours and discard unused portions.[2]

[1]: CDC Shingrix VIS
[2]: Shingrix Prescribing Information (GSK)