Lipitor is a medication used to lower cholesterol levels in the blood. According to the sources provided, there is no evidence to suggest that Lipitor cannot be safely used with exercise. However, it is important to be aware of the potential side effects of Lipitor and to discuss any concerns with a healthcare provider before starting or continuing to take the medication.

The first source [1] provides information about the patent status of Lipitor, but does not directly address the question of whether the medication can be safely used with exercise.

The second source [2] discusses the potential side effects of statins, including Lipitor. These side effects can include muscle pain, weakness, and damage, as well as an increased risk of diabetes and liver damage. However, the article does not suggest that exercise cannot be safely used in conjunction with Lipitor. In fact, the article notes that exercise can help to lower cholesterol levels and reduce the risk of heart disease.

The third source [3] is a FDA drug safety communication that discusses important safety label changes for cholesterol-lowering statin drugs, including Lipitor. The communication notes that statins can cause muscle injury or myopathy, which can be exacerbated by certain medications and activities, such as exercise. However, the communication also notes that the benefits of statins in reducing the risk of heart disease generally outweigh the risks of side effects. The communication recommends that patients who experience muscle pain, weakness, or tenderness while taking statins should contact their healthcare provider immediately.

In summary, there is no evidence to suggest that Lipitor cannot be safely used with exercise. However, it is important to be aware of the potential side effects of Lipitor, including muscle pain, weakness, and damage, and to discuss any concerns with a healthcare provider before starting or continuing to take the medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013
[3] https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-important-safety-label-changes-cholesterol-lowering-statin-drugs