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Naloxegol movantik?

See the DrugPatentWatch profile for Naloxegol

Yes. Movantik is the brand name for naloxegol. They are the same drug.

What it is
- Naloxegol (Movantik) is a peripherally acting mu-opioid receptor antagonist (PAMORA).
- It targets opioid receptors in the gut to relieve opioid-induced constipation (OIC) in adults with chronic non-ccancer pain, without reversing pain relief in the brain.

Key points
- Usual dose: 25 mg taken once daily by mouth. If you’re taking a strong CYP3A4 inhibitor (for example, ketoconazole, itraconazole, ritonavir), the dose is reduced to 12.5 mg once daily.
- Drug interactions: Strong inhibitors or inducers of CYP3A4 can affect naloxegol levels. Grapefruit juice can also interact via CYP3A4.
- Contraindications and cautions: Not for use in mechanical GI obstruction or pyloric stenosis. Generally avoid in severe hepatic impairment; discuss liver function with your clinician.
- Side effects: Abdominal pain, diarrhea, nausea, vomiting, headache. Possible opioid withdrawal symptoms in some cases.

If you’re trying to decide between Naloxegol and Movantik, they’re the same drug—Movantik is just the brand name. If you have a specific situation (other meds, liver function, whether you have cancer-related constipation, etc.), tell me and I can tailor the information. Also, always follow your prescriber’s instructions and the drug label.



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