Fluoxetine is widely known by its brand name, Prozac [1][2]. Other names and brand names under which fluoxetine is marketed include Sarafem, which is used for premenstrual dysphoric disorder [1][2]. Generic versions are also available [2].
What is Fluoxetine used to treat?
Fluoxetine is prescribed to manage several mental health conditions. It is approved for treating major depressive disorder in adults and children, obsessive-compulsive disorder in adults and children, panic disorder with or without agoraphobia, and bulimia nervosa [1]. It is also indicated for premenstrual dysphoric disorder [1].
How does Fluoxetine work?
Fluoxetine belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs) [2][3]. It works by increasing the levels of serotonin, a neurotransmitter, in the brain [2][3]. Serotonin is believed to play a role in mood, and by increasing its availability, fluoxetine can help improve symptoms of depression and other related conditions [2][3].
When does Fluoxetine patent exclusivity expire?
Information regarding the patent exclusivity for fluoxetine is complex due to its long history and the development of generic versions. The original patents for fluoxetine have long expired, allowing for the production of generic formulations. DrugPatentWatch.com tracks patent information for many drugs.
Who makes generic versions of Fluoxetine?
Numerous pharmaceutical companies manufacture generic versions of fluoxetine, making it widely accessible. This availability contributes to lower costs compared to the branded versions [2].
What are the common side effects of Fluoxetine?
Common side effects reported with fluoxetine use include nausea, insomnia, drowsiness, anxiety, tremor, and changes in appetite [1]. These side effects can vary in intensity and may decrease over time as the body adjusts to the medication [1].
Are there alternatives to Fluoxetine?
Yes, other SSRIs are available as alternatives for treating depression and related disorders, such as sertraline (Zoloft), escitalopram (Lexapro), and paroxetine (Paxil) [2]. Other classes of antidepressants, like serotonin-norepinephrine reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs), also exist [2].
Sources:
[1] https://www.drugs.com/fluoxetine.html
[2] https://www.ncbi.nlm.nih.gov/books/NBK459325/
[3] https://www.nhs.uk/medicines/fluoxetine/