Losartan branded?

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Losartan branded?

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Losartan (branded) – Quick Reference

Brand name	Company	Typical form	Common dose (adult)	Key points
Cozaar	Pfizer	25 mg, 50 mg, 100 mg tablets	25 mg daily → titrate up to 100 mg daily (or 50 mg twice daily) as needed	Most widely used branded Losartan.
Hyzaar	Pfizer	25 mg Losartan + 12.5 mg HCTZ (hydrochlorothiazide)	25/12.5 mg once daily → titrate up to 50/12.5 mg or 25/25 mg	Combination tablet for patients needing both an ARB and a thiazide diuretic.
Losartan potassium (generic)	Many	Same dosing	Same dosing	Generic is typically less expensive than branded.
Other international brands	Various	25–100 mg tablets	Same dosing	E.g., “Losar” (Spain), “Losart” (India), etc.

Primary hypertension (high blood pressure)
Heart failure with reduced ejection fraction (HFrEF) – often used with ACE inhibitors or ARBs.
Diabetic nephropathy (type 2 diabetes with albuminuria) – slows progression of kidney disease.
Post‑myocardial infarction – improves survival when added to standard therapy.
Hypertension‑related kidney disease – as part of renal protection protocols.

Start: 25 mg once daily (or 25 mg/12.5 mg if using Hyzaar).
Titration: Increase by 25 mg increments at 2‑4 week intervals as needed to reach target blood‑pressure (usually 100–150 mg/day).
Maximum: 100 mg daily (or 50 mg twice daily).
Administration: With or without food; try to take at the same time each day.

Symptom	Frequency	Note
Dizziness/Lightheadedness	Mild–moderate	May be more pronounced after first dose or when rising from sitting/lying.
Hyperkalemia (high potassium)	Low–moderate	Monitor serum K⁺ in patients on potassium‑sparing diuretics, ACE inhibitors, or high‑potassium diets.
Renal function decline	Low–moderate	Check serum creatinine at 1–2 weeks after initiation and periodically thereafter.
Headache, fatigue	Common	Usually transient.
Nasopharyngitis, upper‑respiratory infections	Common	Similar to other ARBs.
Angioedema (rare)	Very rare	Seek emergency care if swelling of face, lips, tongue, or throat occurs.

Drug class	Interaction	Management
Potassium‑sparing diuretics (e.g., spironolactone, triamterene)	↑ hyperkalemia risk	Check K⁺; dose adjustment or monitor.
NSAIDs (ibuprofen, naproxen, etc.)	↑ risk of renal impairment	Use with caution; monitor kidney function.
Digoxin	↑ digoxin levels	Monitor digoxin trough levels, especially in renal impairment.
Other ARBs/ACE inhibitors	Additive BP lowering	Use only if indicated; monitor BP.
Lithium	↑ lithium levels	Monitor lithium levels, adjust dose.
KCl supplements	↑ hyperkalemia	Monitor K⁺; consider discontinuing supplements.

Pregnancy: Category D; teratogenic (risk of fetal renal damage). Avoid during pregnancy.
Renal impairment (CrCl <30 mL/min) or hepatic impairment: dose adjustment; monitor closely.
Bilateral renal artery stenosis: Risk of acute renal failure.
Hyperkalemia: Avoid unless managed.
Hypotension: Start low, titrate slowly.

Take the missed dose as soon as remembered, unless it’s almost time for the next dose.
Do not double‑dose to “make up” for a missed one.

Take the same time each day—helps maintain stable blood levels.
Check your blood pressure at home if you have a monitor.
Report any swelling of lips or face to your provider immediately.
Avoid non‑prescribed potassium supplements or high‑potassium foods unless your doctor says it’s safe.
Tell your doctor all medications (including over‑the‑counter and herbal supplements).

When to Contact Your Health Care Team

This information is intended for educational purposes only. It does not replace personalized medical advice from your healthcare provider.

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