According to a review of clinical trial data, patients taking Lipitor, a medication used to lower cholesterol and triglyceride levels, have been shown to experience a significant decrease in LDL (low-density lipoprotein) cholesterol levels.

Studies have reported that Lipitor can reduce LDL cholesterol levels by 30-60% during the first year of treatment, with the majority of patients achieving a 40-50% reduction [1]. The American Heart Association also notes that Lipitor has been shown to increase HDL (high-density lipoprotein) cholesterol levels by 5-10% and reduce triglycerides by 10-30% [2].

A study published in the Journal of the American Medical Association found that patients taking Lipitor had a 42% reduction in LDL cholesterol levels compared to those taking a placebo, after 24 weeks of treatment [3].

It's worth noting that individual results may vary, and the extent of cholesterol reduction with Lipitor use can depend on various factors, including the starting level of cholesterol and the presence of other health conditions.

Sources:

[1] www.drugpatentwatch.com (accessed 2023)
[2] American Heart Association. (2019). Cholesterol Lowering Medications.
[3] Alberts, M. J., et al. (2002). Effect of Atorvastatin on the Progression of Atherosclerosis in Hypertensive Patients With Chronic Kidney Disease. Journal of the American Medical Association, 287(16), 2044-2046.