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Lipitor lowers LDL cholesterol, not a protein. LDL stands for low-density lipoprotein. It is a particle that carries cholesterol through the blood. Lipitor works by blocking an enzyme in the liver that makes cholesterol, so less cholesterol gets packaged into LDL particles and sent out into the bloodstream. Why do people call LDL a protein? Lipoproteins contain both lipids and proteins, but the main job of Lipitor is to bring down the lipid level, not the protein component. How does Lipitor fit into statin therapy? Lipitor belongs to the statin class of drugs. Statins are first-line treatment for high cholesterol. They reliably reduce LDL by 20 to 60 percent,具体取决于 the dose. What happens if the LDL level stays high? Persistent high LDL drives plaque buildup in arteries. That process can lead to heart attacks and strokes. Statins like Lipitor reduce those risks by about 25 percent for every 1 mmol/L reduction in LDL. Can other drugs replace Lipitor? Ezetimibe, PCSK9 inhibitors such as Repatha, and bempedoic acid work through different mechanisms and can be used when statins are intolerant or when additional lowering is needed. When does Lipitor lose exclusivity? The patent for Lipitor expired in 2011. Generic atorvastatin is now available worldwide at low cost.
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