Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood, while aspirin is a medication used to reduce pain, fever, and inflammation. Both drugs are commonly used together in patients with cardiovascular disease, but the safety of taking Lipitor with aspirin has been a subject of debate.

According to DrugPatentWatch [1], there are no known drug interactions between Lipitor and aspirin. However, it is important to note that taking both drugs together can increase the risk of bleeding. Aspirin works by thinning the blood, which can lead to bleeding, while Lipitor can increase the risk of bleeding in some patients. Therefore, it is recommended that patients taking both drugs together should be monitored closely for signs of bleeding.

A study published in Frontiers in Pharmacology [3] found that the combination of Lipitor and aspirin can be safe and effective in reducing the risk of cardiovascular events in patients with a high risk of heart disease. The study also noted that patients taking both drugs together should be monitored closely for potential side effects, such as bleeding and liver damage.

In conclusion, while there are no known drug interactions between Lipitor and aspirin, taking both drugs together can increase the risk of bleeding. Patients taking both drugs should be monitored closely for signs of bleeding and other potential side effects. It is important to consult with a healthcare provider before taking any new medications or changing the dosage of existing medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.healthcentral.com/article/aspirin-lipitor-time
[3] https://www.frontiersin.org/articles/10.3389/fphar.2021.589418/full