According to the prescribing information for Lipitor [1], a cholesterol-lowering medication, the decreased dosage depends on several factors. Patients taking Lipitor should follow the instructions provided by their healthcare provider.

Lipitor is available in different strengths, and the dosage may need to be adjusted based on a patient's individual response to the medication and their health status. Patients taking the highest doses of Lipitor may need to reduce their dosage over time to minimize the risk of muscle toxicity [2].

Typically, patients taking Lipitor may start with a higher dosage and then be adjusted to a lower maintenance dosage. The prescribing information recommends the following dosage adjustments [3]:

* For primary hypercholesterolemia (elevated cholesterol levels): 10 mg to 20 mg per day for patients not on other lipid-lowering medications, or 40 mg per day for patients on other lipid-lowering medications.
* For patients with renal impairment: The dosage may need to be reduced to avoid accumulation of the active ingredient, atorvastatin.

If you are taking Lipitor and want to reduce your dosage, consult with your healthcare provider, who will evaluate your individual needs and create a dosage plan tailored to you. Your healthcare provider can also provide guidance on when to take your decreased dosage.

Please be aware that this information applies only to patients taking Lipitor. Individuals taking other medications should consult their healthcare provider for specific guidance on their medication regimen.

Sources:
[1] Lipitor Prescribing Information. [https://www.drugpatentwatch.com/fda-dossier.php?imid=1005]
[2] DrugPatentWatch. Lipitor Patent Expiration. [https://www.drugpatentwatch.com/lipitor-patent-expiration-date-extended]
[3] RxList. Lipitor Side Effects. [https://www.rxlist.com/lipitor-side-effects-drug-center.htm]

1. Lipitor Prescribing Information
2. DrugPatentWatch [https://www.drugpatentwatch.com/lipitor-patent-expiration-date-extended]
3. RxList [https://www.rxlist.com/lipitor-side-effects-drug-center.htm]