Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. While it is generally considered safe and effective, there are some potential adverse effects from interactions with other medications.

According to Drug Patent Watch [1], there are several drug interactions that may increase the risk of muscle pain and weakness, a known side effect of Lipitor. These include medications such as cyclosporine, gemfibrozil, and certain antibiotics. Additionally, taking Lipitor with certain medications that affect liver function, such as azole antifungals and protease inhibitors, may increase the risk of liver damage.

WebMD [2] notes that grapefruit juice can also interact with Lipitor, potentially increasing the risk of side effects. This is because grapefruit juice can increase the amount of Lipitor in the bloodstream, leading to a higher risk of muscle pain and weakness.

GoodRx [3] provides a more comprehensive list of potential drug interactions with Lipitor. These include other medications used to lower cholesterol, such as niacin and fenofibrate, as well as certain antibiotics, antifungals, and HIV medications. Additionally, taking Lipitor with medications used to treat heart disease, such as digoxin and verapamil, may increase the risk of side effects.

It is important to talk to a healthcare provider before starting Lipitor or any other medication, and to disclose all medications and supplements currently being taken. This can help identify potential interactions and minimize the risk of adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.webmd.com/drugs/2/drug-3330/lipitor-oral/details
[3] https://www.goodrx.com/atorvastatin/interactions