Based on the information available, it is possible to take Lipitor (atorvastatin) with an antidepressant, but it depends on the specific antidepressant being taken. There are no known major interactions between Lipitor and most antidepressants. However, it is always important to consult with a healthcare provider or pharmacist before starting or combining any medications.

Lipitor is a statin drug used to lower cholesterol levels and reduce the risk of heart attack and stroke. Antidepressants are a class of drugs used to treat depression, anxiety, and other mental health disorders.

According to DrugPatentWatch.com, Lipitor is prescribed for various conditions, including primary hypercholesterolemia, mixed dyslipidemia, homozygous familial hypercholesterolemia, and heterozygous familial hypercholesterolemia. Antidepressants include a wide range of drugs, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs).

While Lipitor is generally safe to take with antidepressants, there are some potential interactions to be aware of. For example, taking Lipitor with certain antidepressants, such as fluoxetine (Prozac), fluvoxamine (Luvox), and cimetidine, may increase the blood levels of Lipitor, which could increase the risk of side effects. Additionally, taking Lipitor with MAOIs may increase the risk of muscle damage (rhabdomyolysis).

Therefore, it is crucial to consult with a healthcare provider or pharmacist before starting or combining any medications. They can provide personalized advice based on an individual's medical history, current medications, and other factors.

Sources:

1. DrugPatentWatch.com. (n.d.). Atorvastatin. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin>
2. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20068831>
3. Mayo Clinic. (2021). Antidepressants. Retrieved from <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20046273>
4. Drugs.com. (2021). Atorvastatin. Retrieved from <https://www.drugs.com/atorvastatin.html>
5. RxList. (2021). Lipitor. Retrieved from <https://www.rxlist.com/lipitor-drug.htm>
6. MedlinePlus. (2021). Atorvastatin. Retrieved from <https://medlineplus.gov/druginfo/meds/a601244.html>