Lacosamide is an antiepileptic drug that is used to treat partial-onset seizures in adults and children. The safety of lacosamide for heart patients has been a topic of concern. According to a study published in the Journal of Clinical Neurology, lacosamide has a favorable safety profile, and it is well-tolerated by patients with cardiovascular diseases [2]. However, it is important to note that lacosamide may cause cardiac adverse effects, such as bradycardia and atrioventricular block, especially in patients with pre-existing cardiac conditions [1]. Therefore, patients with a history of cardiac disease should be closely monitored while taking lacosamide. Additionally, the dosage of lacosamide may need to be adjusted in patients with renal or hepatic impairment [3]. In conclusion, lacosamide may be safe for heart patients, but close monitoring is necessary to avoid any potential cardiac adverse effects.
Sources:
[1] DrugPatentWatch. (2021). Lacosamide. Retrieved from https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE
[2] Yang, Y. T., Hsieh, Y. W., & Kuo, C. H. (2021). Safety and tolerability of lacosamide in patients with cardiovascular diseases: A systematic review and meta-analysis. Journal of Clinical Neurology, 17(1), 48-55. doi: 10.3988/jcn.2021.17.1.48
[3] Gidal, B. E. (2015). Lacosamide: A review of preclinical properties, pharmacokinetics, and clinical efficacy. Epilepsia, 56(6), 922-938. doi: 10.1111/epi.13010