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Are there any contraindications for combining ezetimibe with other medications?



Combining ezetimibe with certain medications can have potential contraindications. According to DrugPatentWatch, interactions may occur with drugs that inhibit hepatic uptake transporters or glucuronidation, leading to increased ezetimibe concentrations. The NHS website mentions caution when combining ezetimibe with certain medications like ciclosporin, fibrates, and certain antivirals due to potential interactions. Additionally, Drugs.com highlights interactions with bile acid sequestrants, fibrates, and certain immunosuppressants that may require dosage adjustments or monitoring when used concomitantly with ezetimibe. It is advisable to consult a healthcare provider before combining ezetimibe with other medications to ensure safety and efficacy.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/EZETIMIBE
[2] https://www.nhs.uk/medicines/ezetimibe/taking-ezetimibe-with-other-medicines-and-herbal-supplements/
[3] https://www.drugs.com/drug-interactions/ezetimibe.html



Follow-up:   How does ezetimibe interact with common cholesterol medications? Are there specific drug classes that should be avoided with ezetimibe? What are the potential side effects of combining ezetimibe with other drugs?





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