Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs called statins, which work by inhibiting an enzyme in the liver that produces cholesterol [1].

According to a study published in Lipids in Health and Disease, atorvastatin has been shown to be effective in reducing cholesterol levels in patients with high-fat diets [2]. The study found that atorvastatin was able to significantly reduce total cholesterol, LDL cholesterol, and triglyceride levels in patients with hyperlipidemia (high levels of lipids in the blood) who were consuming a high-fat diet. The study also found that atorvastatin was well-tolerated by patients and had a low incidence of side effects [2].

Another study published in the Journal of Lipid Research found that atorvastatin was effective in reducing cholesterol levels in mice fed a high-fat diet [3]. The study found that atorvastatin was able to reduce total cholesterol, LDL cholesterol, and triglyceride levels in the mice, and also prevented the development of atherosclerosis (hardening and narrowing of the arteries) [3].

In conclusion, both studies suggest that atorvastatin, or Lipitor, is effective in reducing cholesterol levels in patients with high-fat diets. However, it is important to note that medication should not be the only approach to managing high cholesterol levels. A healthy diet and regular exercise are also important factors in maintaining healthy cholesterol levels [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-10-23
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027324/