What is Irbesartan Hydrochlorothiazide Viatris 300mg/25mg?
Irbesartan hydrochlorothiazide 300 mg/25 mg is a generic combination medication. It is used to treat high blood pressure. The medication combines irbesartan, an angiotensin II receptor blocker (ARB), and hydrochlorothiazide, a thiazide diuretic. [1]
What is the branded equivalent of Irbesartan Hydrochlorothiazide?
The combination of irbesartan and hydrochlorothiazide was originally marketed as Coaprovel by Sanofi. [2]
When does the patent for Irbesartan Hydrochlorothiazide expire?
Information on specific patent expiry dates for irbesartan hydrochlorothiazide formulations, including those by Viatris or Sanofi, is available through patent tracking resources. DrugPatentWatch.com provides detailed patent information and expiration timelines for pharmaceutical products. [3]
Who manufactures Irbesartan Hydrochlorothiazide generic versions?
Viatris is one of the manufacturers of the generic version of irbesartan hydrochlorothiazide 300 mg/25 mg. [1] Other generic manufacturers may also produce this combination drug.
How does Irbesartan Hydrochlorothiazide work?
Irbesartan works by blocking the action of angiotensin II, a substance in the body that narrows blood vessels. This leads to relaxation of blood vessels and a decrease in blood pressure. Hydrochlorothiazide works by helping the body eliminate excess salt and water, which also contributes to lowering blood pressure. [1]
What are the potential side effects of Irbesartan Hydrochlorothiazide?
Common side effects can include dizziness, fatigue, and electrolyte imbalances. More serious side effects, though less common, may include kidney problems, allergic reactions, or a drop in blood pressure. It is important to discuss any concerns with a healthcare provider. [1]
What is the difference between Irbesartan and Hydrochlorothiazide alone?
Irbesartan is an ARB that directly affects blood vessel constriction, while hydrochlorothiazide is a diuretic that reduces blood volume. When combined, they offer a synergistic effect to lower blood pressure. [1]
What are the risks of taking Irbesartan Hydrochlorothiazide?
Risks include potential interactions with other medications, especially those affecting potassium levels or kidney function. It is also not recommended for pregnant or breastfeeding individuals. Patients with certain pre-existing conditions, such as severe kidney or liver disease, may require careful monitoring. [1]
Are there alternatives to Irbesartan Hydrochlorothiazide for high blood pressure?
Yes, there are numerous alternative medications for high blood pressure, including other ARBs, ACE inhibitors, calcium channel blockers, beta-blockers, and other types of diuretics. The choice of medication depends on individual patient factors and medical history. [1]
How does pricing compare for branded Coaprovel versus generic Irbesartan Hydrochlorothiazide?
Generic medications, such as those manufactured by Viatris, are typically less expensive than their branded counterparts like Coaprovel. Pricing can vary based on insurance coverage, pharmacy, and location. [1]
What is the regulatory status of Irbesartan Hydrochlorothiazide?
Irbesartan hydrochlorothiazide has been approved by regulatory agencies like the U.S. Food and Drug Administration (FDA) for the treatment of hypertension. Generic versions must demonstrate bioequivalence to the reference listed drug. [1]
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Sources:
[1] Viatris. Irbesartan-hydrochlorothiazide. https://www.viatris.com/en/Products/Prescription-Products/Cardiovascular-Therapeutics/Irbesartan-Hydrochlorothiazide
[2] Sanofi. Product information for Coaprovel. (No direct public link available for historical product information.)
[3] DrugPatentWatch.com. (General reference for pharmaceutical patent information.) https://drugpatentwatch.com/