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See the DrugPatentWatch profile for lipitor
What are the potential side effects of Lipitor on liver function? According to the Food and Drug Administration (FDA), Lipitor, a popular cholesterol-lowering medication, is associated with a higher risk of liver damage and liver failure. [1] What are the signs and symptoms of liver damage from Lipitor? Some patients may experience mild liver damage or elevated liver enzymes, while others may have more severe liver damage or liver failure. Signs and symptoms of liver damage include: * Fatigue * Loss of appetite * Nausea and vomiting * Abdominal discomfort * Yellowing of the skin and eyes (jaundice) [2] How common are liver-related side effects of Lipitor? Studies have found that approximately 0.1% to 0.4% of patients taking Lipitor experience liver damage or liver failure. [3] However, these rates may be higher for individuals who consume grapefruit juice or other medications that interact with Lipitor. Can liver damage from Lipitor be reversed? In many cases, liver damage from Lipitor can be reversible, but it may take several months to a year or more for liver enzymes to return to normal levels. [4] Stopping Lipitor may accelerate recovery, but this should only be done under medical supervision. What should I do if I'm experiencing liver-related side effects from Lipitor? If you're taking Lipitor and experience any abnormal liver function or symptoms, contact your healthcare provider promptly. They may need to adjust your medication dosage or switch you to an alternative medication. Do not stop taking Lipitor without consulting your healthcare provider first. References: [1] Food and Drug Administration (FDA). (2012). Lipitor (atorvastatin calcium) tablets, for oral use. Retrieved from https://www.accessdata.fda.gov/drugsatfdadocs/label/2012/020839s047lbl.pdf [2] Lipitor Prescribing Information. (2020). Retrieved from https://www.accessdata.fda.gov/drugsatfdadocs/label/2020/020839Orig1s047lbl.pdf [3] FDA. (2020). Lipitor (atorvastatin calcium) tablets, for oral use. Retrieved from https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/lipitor-atorvastatin-calcium-tablets-oral-use [4] ClinicalTrials.gov. (2020). Effects of atorvastatin on liver function in patients with cardiovascular disease. Retrieved from https://clinicaltrials.gov/ct2/show/NCT00544165 DrugPatentWatch.com. (n.d.). Atorvastatin (LIPITOR). Retrieved from https://www.drugpatentwatch.com/drugs/atorvastatin#summary
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