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See the DrugPatentWatch profile for Kisqali
Kisqali (ribociclib) is a CDK4/6 inhibitor used for HR-positive, HER2-negative advanced or metastatic breast cancer. It’s given in combination with hormonal therapy. Typical approved uses include: - In postmenopausal women: ribociclib plus letrozole as initial endocrine therapy for HR+/HER2− advanced or metastatic breast cancer. - In patients who have progressed after prior endocrine therapy: ribociclib plus fulvestrant. - In premenopausal or perimenopausal women (in combination with tamoxifen and goserelin) for HR+/HER2− advanced or metastatic breast cancer (based on specific regional approvals). Notes: - Not approved for HER2-positive or triple-negative breast cancer. - Exact indications can vary by country; always check the local labeling and consult a clinician for individual treatment decisions.
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