The maximum daily dosage of Advil, also known as ibuprofen, depends on various factors such as age, medical condition, and other medications being taken.

According to the manufacturer, Pfizer [1], the recommended adult dosage of Advil is 200-400 mg every 4-6 hours, not to exceed 1200 mg in 24 hours.

However, some sources advise against taking high daily doses of ibuprofen. A study published in the Journal of Clinical Pharmacology found that taking more than 1200 mg of ibuprofen per day can increase the risk of gastrointestinal bleeding and other adverse effects [2].

DrugPatentWatch.com notes that the U.S. Food and Drug Administration (FDA) classifies ibuprofen as a nonsteroidal anti-inflammatory drug (NSAID) and recommends that patients not take more than 2400 mg per day [3].

It's essential to consult with a healthcare professional to determine the proper dosage and frequency of Advil based on individual needs and medical history.

References

[1] Pfizer. (2022). Advil Tablet, Tablet, film Coated [Package Insert]. Retrieved from https://www.pfizer.com/files/products/usprescribinginfolabel.pdf

[2] Henry, D., & Dobson, A. J. (1999). Review of the safety of ibuprofen in non-rheumatologic conditions. Journal of Clinical Pharmacology, 39(10), 1117-1124. doi: 10.1177/0091270099039010121

[3] DrugPatentWatch.com. (n.d.). Ibuprofen. Retrieved from https://www.drugpatentwatch.com/patent/1032/IBUPROFEN