Orserdu dosing?

Orserdu (elacestrant) dosing (for adults with ER+/HER2− advanced or metastatic breast cancer):

Usual dose

• 345 mg by mouth once daily
• Continue until disease progression or unacceptable toxicity.

If a dose is missed

• Take it as soon as possible the same day.
• Do not take two doses to make up for a missed one.
• Resume the next day at the usual time.

Dose modifications (important)

Orserdu dosing can change with side effects (especially elevated liver enzymes or worsening adverse effects) and with drug interactions (particularly strong CYP3A inhibitors/inducers). Common practice is dose interruption first, then resume at a reduced dose if appropriate—typically down to 258 mg once daily (and potentially further, per the specific label/clinician plan).

Drug interaction considerations

• Avoid strong CYP3A inducers (can lower elacestrant levels).
• Use caution/adjust as needed with strong CYP3A inhibitors (can raise levels).

If you tell me (1) your cancer setting (advanced/metastatic), (2) current dose, and (3) any other meds you take (especially antifungals/antibiotics/antiseizure meds), I can help confirm the most relevant dosing and adjustment for your situation.