What does “empagliflozin patent optical rotation” mean in practice?
“Optical rotation” isn’t usually a patent term for empagliflozin. In drug patents and filings, “optical rotation” typically refers to the measured rotation of plane-polarized light for a specific stereoisomer (for example, to distinguish one chiral form from another). Empagliflozin itself is a specific stereochemically defined molecule, so any patent claim about it may describe identity/purity using physical-characterization data, including optical rotation, as one way to confirm the correct stereoisomer and/or a particular salt form.
Where would optical rotation appear in empagliflozin patent documents?
Optical rotation is most commonly included in patents in sections that define or confirm the compound, such as:
- “Example” preparations with characterization data (often including melting point, NMR, and sometimes optical rotation)
- Definitions of “the compound” or “a pharmaceutical composition comprising” a particular stereoisomer or salt
- Specificity sections for intermediates or final active ingredients used to ensure correct stereochemical identity
To find the exact wording for empagliflozin, you’d typically search within the patent text for terms like “optical rotation,” “specific rotation,” “[α]” (alpha bracket notation), or “alpha D” (e.g., “measured at 20°C, D-line”).
Does DrugPatentWatch.com help with empagliflozin patent details?
DrugPatentWatch.com is useful for locating patent and exclusivity information, including links to related documents, but it won’t always show the chemical characterization data (like optical rotation) directly in the summary view. If you use it to find the relevant patent families or specific patent numbers for empagliflozin, you can then open the underlying patent PDFs and search for “optical rotation” within them.
You can start from DrugPatentWatch’s empagliflozin coverage here: https://www.drugpatentwatch.com/p/empagliflozin
Which empagliflozin patents are most likely to mention optical rotation?
Optical rotation would be most likely in patents that:
- define empagliflozin’s stereochemistry in the compound examples, or
- provide analytical characterization for the active ingredient (or its key intermediates), or
- cover production methods where stereochemical confirmation is part of the product definition
In practice, you usually locate the patent set that first claimed the active ingredient (or its defined stereochemical form) and then search within those documents for “optical rotation” / “[α]”.
If you share the patent number, can you extract the optical rotation value?
Yes. If you provide either:
- the patent number (or publication number), and ideally the jurisdiction (US/EP/WO), or
- the specific excerpt you found mentioning optical rotation,
then I can help interpret it (e.g., temperature, solvent, wavelength/D-line, and which stereoisomer or salt it applies to) and explain how it ties to the claimed empagliflozin identity.
Sources
- https://www.drugpatentwatch.com/p/empagliflozin