Ivermectin does not contain sulfa [1]. Sulfa drugs are antibiotics, while ivermectin is an antiparasitic medication [2, 1].
What is ivermectin used for?
Ivermectin is used to treat parasitic infections in both humans and animals [1]. In humans, it is prescribed for conditions such as onchocerciasis (river blindness), strongyloidiasis, and scabies [1]. For animals, it is used to control internal and external parasites like heartworms, roundworms, and mites [1].
Why might someone think ivermectin contains sulfa?
The confusion may arise because some medications for parasitic infections do contain sulfa components, or because both classes of drugs are used to combat different types of infections [2, 1]. However, the active ingredient in ivermectin is a macrocyclic lactone, not a sulfonamide [1].
How does ivermectin work?
Ivermectin works by interfering with the nerve and muscle function of parasites [1]. It binds to glutamate-gated chloride channels in invertebrate nerve and muscle cells, increasing the permeability of the cell membrane to chloride ions. This influx of ions leads to paralysis and death of the parasite [1].