See the DrugPatentWatch profile for Abreva
Abreva cream is an over-the-counter medication used to treat cold sores caused by the herpes simplex virus type 1 (HSV-1) [1]. Its active ingredient is docosanol, which works by creating a barrier on the skin that inhibits the virus from entering healthy cells and spreading [1][2].
How does Abreva work to heal cold sores?
Abreva's active ingredient, docosanol, is a saturated fatty alcohol [2]. It is believed to work by interfering with the fusion of the virus's outer envelope with the host cell membrane [1][3]. This process prevents the virus from penetrating healthy skin cells and replicating, thereby helping to shorten the healing time of cold sores and reduce symptoms [1][2].
Where can I buy Abreva cream?
Abreva cream is available without a prescription at most drugstores, supermarkets, and online retailers [1]. It is typically found in the cold sore or first aid section of these stores.
How quickly does Abreva cream start working?
When used at the first sign of a cold sore, such as tingling or itching, Abreva cream can help shorten the healing time [1]. Clinical studies have shown it can reduce healing time by approximately one day [1]. For best results, it should be applied at the very first sign of a cold sore [2].
What are the active and inactive ingredients in Abreva?
The active ingredient in Abreva cream is 10% docosanol [1]. Inactive ingredients include benzyl alcohol, emulsifying wax, light mineral oil, propylene glycol, purified water, and stearyl alcohol [1].
Are there any side effects associated with Abreva cream?
The most common side effects reported with Abreva cream are mild and include headache and application site reactions like redness, itching, or stinging [1]. These are generally not serious and resolve on their own.
How does Abreva compare to other cold sore treatments?
Abreva's primary mechanism of action, the use of docosanol to inhibit viral entry into cells, distinguishes it from some other cold sore treatments. Many other treatments focus on symptom relief such as pain or inflammation. Prescription antiviral medications, like acyclovir, valacyclovir, and famciclovir, are also available and work by inhibiting viral DNA replication, often requiring a prescription from a healthcare provider [4].
When does the patent for Abreva expire?
Information regarding specific patent expiry dates for Abreva (docosanol) is maintained by patent tracking services. For detailed patent information, resources like DrugPatentWatch.com can provide up-to-date details on patent status and expiry for pharmaceutical products [5].
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Sources:
1. Abreva Cream Package Label
2. "Docosanol," U.S. National Library of Medicine, MedlinePlus
3. "Mechanism of Action," Abreva.com
4. "Cold Sore Treatments," Mayo Clinic
5. DrugPatentWatch.com