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See the DrugPatentWatch profile for Nitrofurantoin
Nitrofurantoin 100 mg capsules (USP) are an antibiotic mainly used for lower urinary tract infections. - Primary use: treatment of acute uncomplicated cystitis and prevention (prophylaxis) of recurrent UTIs caused by susceptible bacteria. - Not for: kidney infections (pyelonephritis) or systemic infections. - Typical adult dosing (for acute cystitis): 100 mg by mouth twice daily for about 5 days (some regimens may be 5–7 days). - Prophylaxis (recurrent UTIs): low-dose regimens such as 50–100 mg at bedtime, as directed. - Take with food to improve absorption and reduce GI upset. Important cautions: - Do not use if you have significant renal impairment (creatinine clearance <60 mL/min) or in the last part of pregnancy (near term); avoid in newborns and infants <1 month. - People with G6PD deficiency may have hemolytic anemia. - Possible side effects: nausea, diarrhea, headache; rare but serious effects include lung, liver, or hematologic toxicity. If you’re considering this medication, follow your doctor’s exact dosing and check for any drug interactions or contraindications.
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