See the DrugPatentWatch profile for lisinopril
Lisinopril is a generic medication used to treat high blood pressure and heart failure. It is also prescribed to improve survival after a heart attack [1]. The brand name drug for which lisinopril is the generic is Prinivil and Zestril [2].
When does the patent for Prinivil or Zestril expire?
The original patents for Prinivil and Zestril have long since expired. This has allowed for the widespread availability of generic lisinopril. DrugPatentWatch.com tracks patent information for pharmaceuticals, and typically, branded drugs have patents that expire, leading to the introduction of generic versions [3].
How does lisinopril work?
Lisinopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors [1]. ACE inhibitors work by relaxing blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood [1][4].
What are the uses of lisinopril?
Lisinopril is prescribed for several cardiovascular conditions:
* High Blood Pressure (Hypertension): It helps lower elevated blood pressure, reducing the risk of stroke and heart attack [1].
* Heart Failure: By reducing the workload on the heart, lisinopril can improve symptoms and prognosis in patients with heart failure [1].
* Post-Heart Attack: It is used to improve survival rates and reduce the risk of future heart problems in individuals who have experienced a heart attack [1].
What are common side effects of lisinopril?
Common side effects of lisinopril can include dizziness, headache, and fatigue [5]. Less common but more serious side effects may involve a persistent dry cough, swelling of the face, lips, tongue, or throat, and kidney problems [5]. It is important for patients to discuss any side effects with their healthcare provider.
Are there other ACE inhibitors similar to lisinopril?
Yes, there are other ACE inhibitors available. Examples include enalapril, ramipril, and benazepril [6]. While they belong to the same drug class and share similar mechanisms of action, there can be differences in their dosing, side effect profiles, and how they are metabolized by the body [6].
Can I switch between brand-name Prinivil/Zestril and generic lisinopril?
Patients can generally switch between brand-name Prinivil/Zestril and generic lisinopril, as they are considered therapeutically equivalent [7]. However, it is always advisable to consult with a doctor or pharmacist before making any changes to medication to ensure it is appropriate for your individual health needs.
Sources:
1. https://www.drugpatentwatch.com/drug/lisinopril
2. https://www.drugpatentwatch.com/blog/understanding-drug-patents-and-exclusivity
3. https://www.drugpatentwatch.com/
4. https://www.nhs.uk/medicines/lisinopril/
5. https://www.mayoclinic.org/drugs-supplements/lisinopril-oral-route/side-effects/drg-20071050
6. https://www.nhs.uk/medicines/lisinopril/other-medicines-in-this-class/
7. https://www.fda.gov/drugs/generic-drugs/what-generic-drugs