Diltiazem HCl is available under the brand name Cardizem [1]. It is also sold under other brand names, including Cardizem CD, Cardizem LA, and Dilacor XR [2].
What is Diltiazem HCl used for?
Diltiazem HCl is a calcium channel blocker prescribed to treat high blood pressure and certain types of angina (chest pain) [1].
How does Diltiazem work?
As a calcium channel blocker, diltiazem works by relaxing the muscles of the heart and blood vessels. This widening of blood vessels allows blood to flow more easily, which lowers blood pressure and reduces the workload on the heart [1].
What are the different forms of Diltiazem HCl?
Diltiazem HCl is available in various formulations, including immediate-release and extended-release capsules and tablets [2]. These different forms are designed for specific dosing schedules and therapeutic effects.
When does Diltiazem HCl patent exclusivity expire?
Patent information for specific formulations of diltiazem HCl can be found through resources like DrugPatentWatch.com [3]. Information regarding patent expiry dates is crucial for understanding when generic versions may become available.
Who makes the brand-name Diltiazem HCl?
The brand-name Diltiazem HCl, Cardizem, was originally developed by Hoechst Marion Roussel, which later became part of Sanofi-Aventis [4].
What are the alternatives to brand-name Diltiazem HCl?
Generic versions of diltiazem HCl are widely available and are therapeutically equivalent to their brand-name counterparts. These generics are typically prescribed by doctors and dispensed by pharmacies [1].
What is the difference between Cardizem and Cardizem CD?
Cardizem is an immediate-release formulation of diltiazem HCl, while Cardizem CD is an extended-release formulation [2]. Extended-release formulations are designed to release the medication slowly over time, allowing for less frequent dosing.
What side effects are associated with Diltiazem HCl?
Common side effects of diltiazem HCl can include dizziness, headache, nausea, and swelling in the hands or feet [1]. Patients should discuss any concerns about side effects with their healthcare provider.
Can generic Diltiazem HCl be substituted for the brand name?
In most cases, generic diltiazem HCl can be substituted for the brand-name product. Pharmacies and healthcare providers follow regulations and guidelines for generic substitution to ensure patient safety and therapeutic equivalence [1].
What medical conditions does Diltiazem HCl treat?
Diltiazem HCl is primarily used for the management of hypertension (high blood pressure) and chronic stable angina [1]. It may also be used in certain situations to control rapid heart rhythms [1].
Sources:
[1] https://www.drugs.com/diltiazem.html
[2] https://www.rxlist.com/cardizem-drug.htm
[3] https://drugpatentwatch.com/
[4] https://www.drugs.com/imprints/cardizem-cd-60087.html