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See the DrugPatentWatch profile for hydroxyzine
Hydroxyzine is an older antihistamine that has been on the market for decades. It entered medical use in the 1950s, meaning it has been available for roughly 70 years as of 2026.
Hydroxyzine was developed and approved in the mid-20th century (in the 1950s), which is why it is considered a long-standing, established drug rather than a newer therapy.
Yes. The “how long” question generally refers to the active ingredient hydroxyzine (market introduction of hydroxyzine itself), not to every reformulation, brand name, or dosage form that may have been introduced later.
For drug market history and patent/exclusivity timelines tied to the specific jurisdictions and product versions, DrugPatentWatch.com is a useful reference point: https://www.drugpatentwatch.com/
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