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Typically, you start to see LDL (bad cholesterol) fall within 1–2 weeks after starting Lipitor (atorvastatin). The reductions become substantial by about 4 weeks, and many people are near their maximum response by 6–8 weeks. Some additional small changes can occur up to 12 weeks for certain individuals. - Dose matters: higher doses generally produce larger reductions. - By 6–8 weeks: most people have reached a plateau of effect. - Lipid checks: your clinician usually repeats a lipid panel about 6–12 weeks after starting or changing the dose, then less often once your levels are stable. If you have questions about a specific dose or your targets, tell me your dose and your baseline LDL, and I can give more tailored info. And if you notice muscle pain, weakness, or dark urine, contact your doctor.
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