What are the common side effects of Remicade (infliximab)?
Remicade can cause side effects in multiple body systems. Commonly reported issues include infusion-related reactions and infections. Patients may experience symptoms such as fever, chills, cough or other cold-like symptoms, and feeling unwell around the time of infusions. [1]
What serious side effects should people watch for?
Remicade carries risks that can be serious, including infections that may become life-threatening. Patients should seek urgent medical care if they develop signs of severe infection (for example, high fever, worsening shortness of breath, or feeling rapidly worse). [1]
There are also concerns about immune-related complications and blood-related problems that require prompt evaluation if symptoms occur. [1]
How do infusion reactions show up?
Because Remicade is given through an IV infusion, some people can have reactions during or shortly after treatment. These may include symptoms like fever, chills, rash, shortness of breath, or low/high blood pressure. Clinicians monitor closely during infusions, and reactions may lead to stopping treatment or adjusting the regimen. [1]
Can Remicade increase the risk of infections, including tuberculosis?
Yes. Remicade suppresses parts of the immune system, which can increase the risk of infections, including tuberculosis. For that reason, prescribers typically screen for TB and other risk factors before starting treatment and monitor during therapy. [1]
Who is more at risk for side effects?
Risk tends to be higher in people who are more prone to infections or who have certain underlying conditions, including chronic infections or significant immune suppression. The prescriber’s screening and monitoring plan is designed to reduce these risks. [1]
What side effects should be reported right away?
People using Remicade should report new or worsening symptoms quickly, especially:
- signs of infection (fever, persistent cough, painful urination, worsening fatigue)
- severe infusion or allergic-type symptoms during/after an infusion
- any symptoms that suggest a serious reaction or infection complications [1]
Are there alternatives if Remicade side effects are a problem?
Switching within the same drug class or to a different biologic may be considered if side effects are unacceptable. The choice depends on the condition being treated (such as Crohn’s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis) and the specific side effect profile. Side effects and risk factors are central to that decision. [1]
Sources
[1] Remicade (infliximab) side effects and safety information (Drug info resource via Drugs.com): https://www.drugs.com/remicade.html