Lipitor (atorvastatin) is a medication that belongs to a class of drugs called statins. It is used to lower cholesterol levels in the blood and reduce the risk of heart attack, stroke, and other heart-related problems. According to WebMD [2], Lipitor should be taken with a full glass of water, once a day, with or without food. However, the drug patent watch [1] doesn't specify whether Lipitor should be taken with food or not.

While it is recommended to take Lipitor with a full glass of water, the sources do not indicate that it needs to be taken with high-fat meals. In fact, it is generally recommended to avoid high-fat meals when taking Lipitor [3]. This is because high-fat meals can increase the absorption of the drug and increase the risk of side effects such as muscle pain and liver damage.

However, it is important to note that Lipitor should not be taken with grapefruit or grapefruit juice, as it can increase the risk of side effects [2]. Additionally, it is important to follow the dosage instructions provided by your doctor and not to make any changes to your medication regimen without consulting with them first.

In conclusion, while the sources do not specifically mention whether Lipitor can be taken with low-fat meals, it is generally recommended to avoid high-fat meals when taking this medication. It is important to follow the dosage instructions provided by your doctor and not to make any changes to your medication regimen without consulting with them first.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.webmd.com/drugs/2/drug-3330/lipitor-oral/details
[3] https://www.singlecare.com/blog/atorvastatin-alternatives/