Methotrexate, a medication commonly used to treat various conditions such as cancer, rheumatoid arthritis, and psoriasis, comes with certain risks and side effects. According to Drug Patent Watch, some potential risks associated with methotrexate include liver damage, lung problems, bone marrow suppression, and gastrointestinal issues. The National Center for Biotechnology Information mentions that methotrexate can cause adverse effects on the liver, lungs, kidneys, and blood cells. MedlinePlus highlights that methotrexate may lead to nausea, vomiting, dizziness, and headaches. It is crucial for patients taking methotrexate to be closely monitored by healthcare professionals to manage these risks effectively.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/METHOTREXATE
[2] https://www.ncbi.nlm.nih.gov/books/NBK556114/
[3] https://medlineplus.gov/druginfo/meds/a682019.html