How often do polivy's most frequent side effects occur?

Polivy (polatuzumab vedotin) has a known set of “most common” side effects, but the exact frequency depends on the clinical trial and patient population. In general, the way it’s reported is as a percentage of people who experienced each side effect (often “any grade,” not just severe cases).

Most frequent side effects reported with Polivy include:
- Low white blood cell count / neutropenia (very common)
- Infections (common)
- Peripheral neuropathy (common)
- Anemia and thrombocytopenia (common)
- Nausea and diarrhea (common)
- Fatigue and fever (common)

To answer your question precisely—“how often”—I need one detail because Polivy’s prescribing information lists several frequencies (e.g., “any grade” vs “grade 3 or 4,” and by regimen).

Which situation are you asking about?
1) Relapsed/refractory DLBCL (Polivy + bendamustine + rituximab), or
2) Another regimen/setting (if you know it)?

If you tell me the setting (or paste the side effects you’re most concerned about), I can give the exact percentages from the label for each one.