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Trade name for tizanidine?

See the DrugPatentWatch profile for tizanidine

What’s the official brand name of tizanidine in the United States?
Tizanidine is sold in the U.S. under the brand name Zanaflex. The FDA lists Zanaflex as the approved brand‑name formulation of tizanidine. [1]

Are there other brand names used around the world?
Outside the United States, tizanidine is often marketed under its generic name or other regional brand names. In Canada, it is commonly sold as Tizanidine; in the United Kingdom it appears under the brand Tizanid. These variations depend on the local regulatory approvals and marketing agreements. [2][3]

Which companies market the brand‑name drug?
The original manufacturer of Zanaflex was Zynerba Pharmaceuticals, which filed the approval in 1992. Since then, several generic manufacturers have produced tizanidine once patents expired, but the brand‑name product remains under the stewardship of the original developer. [4]

When did the brand name receive FDA approval?
Zanaflex received its initial FDA approval in 1992 as the first branded tizanidine product, establishing it as the reference formulation for the drug class. [1]

Can I buy tizanidine as a generic drug?
Yes. Generic versions of tizanidine entered the market after the patent protection of the brand name expired. These generics are chemically identical to Zanaflex and are available from multiple manufacturers, often at lower cost. [5]

How do price and availability differ between the brand and generics?
The brand‑name Zanaflex typically costs 2–3 times more than the generic equivalents. Availability of the brand is limited to specialty pharmacies and certain hospitals, whereas generics are widely distributed through retail pharmacies, making them more accessible for most patients. [5][6]

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Sources
[1] https://en.wikipedia.org/wiki/Tizanidine
[2] https://www.drugs.com/nda/zanaflex.html
[3] https://www.drugs.com/monograph/tizanidine.html
[4] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020102s019lbl.pdf
[5] https://www.drugs.com/monograph/tizanidine.html
[6] https://www.mayoclinic.org/drugs-supplements/tizanidine-oral-route/description/drg-20066441



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