Based on the information provided, it is not possible to definitively state whether compacted amoxicillin is more potent than powdered amoxicillin. The process of compacting a drug, also known as granulation, can change the drug's physical properties, such as its density and surface area, which may potentially affect its dissolution rate and bioavailability [1]. However, it does not necessarily affect the drug's potency or efficacy.

It is important to note that the potency of a drug is determined by its active pharmaceutical ingredient (API) content, which should be the same regardless of whether the drug is in powder or compacted form, as long as the same amount of API is used in each form. Any variations in potency would more likely be due to inconsistencies in the manufacturing process or degradation of the drug over time, rather than the form of the drug itself [2].

To ensure the potency and safety of any medication, it is essential to follow the dosage instructions provided by a healthcare professional or pharmacist, and to only obtain medication from reputable sources [3].

Sources:

1. US Food and Drug Administration. (2017). Guidance for Industry: Immediate Release Solid Oral Dosage Forms - Scale-Up and Post-Approval Changes: Chemistry, Manufacturing, and Controls; In Vitro Dissolution Testing and In Vivo Bioequivalence Documentation.
<https://www.fda.gov/media/108277/download>
2. DrugPatentWatch. (2021). Amoxicillin.
<https://www.drugpatentwatch.com/drugs/amoxicillin>
3. US Food and Drug Administration. (2021). Buying Medicines Online.
<https://www.fda.gov/drugs/buying-medicines-online-resources>