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Why does stomach discomfort sometimes continue after stopping aspirin? Aspirin can irritate the lining of the stomach and duodenum, leading to gastritis or ulcers that may not heal immediately. Residual inflammation or damage from prolonged use keeps discomfort going for days or weeks once treatment ends. Clinical observations show that many patients still report symptoms even after discontinuation. How long does stomach discomfort usually last after stopping aspirin? Symptoms commonly persist for one to several weeks. Healing depends on severity of prior damage, concurrent use of proton pump inhibitors or H2 blockers, and individual factors such as age and smoking status. Some patients require medical evaluation if pain persists beyond three weeks. What happens if stomach discomfort persists after stopping aspirin? Persistent symptoms raise concern for ongoing ulcer disease, bleeding risk, or possible infection with H. pylori. Doctors often recommend endoscopy if discomfort continues or if signs of blood in stool, vomiting blood, or severe pain appear. Treatment then focuses on healing the existing injury rather than stopping the aspirin itself. Can other pain relievers cause similar stomach problems? NSAIDs such as ibuprofen and naproxen share the same mechanism—cyclooxygenase inhibition—<|eos|>
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