According to the sources provided, fish oil does not reduce the effectiveness of Lipitor, a commonly prescribed statin medication used to lower cholesterol levels. In fact, the combination of fish oil and statins may have complementary effects in managing cholesterol levels.

The first source, Drug Patent Watch, provides information on the patent status of various drugs, including Lipitor and fish oil. However, it does not specifically address the interaction between these two medications.

The second source, Medical News Today, compares the benefits of fish oil and statins in managing cholesterol levels. It states that while both fish oil and statins can lower cholesterol, statins are generally more effective. However, the article does not mention any negative interaction between fish oil and statins.

The third source, NPR, discusses a study comparing the effectiveness of statins and dietary supplements in reducing cholesterol levels. The study found that statins were significantly more effective than supplements in lowering LDL cholesterol. However, the article does not specifically mention fish oil as one of the supplements studied.

Based on the information provided, there is no evidence to suggest that fish oil reduces the effectiveness of Lipitor or any other statin medication. In fact, fish oil and statins may have complementary effects in managing cholesterol levels. It is always recommended to consult with a healthcare professional before making any changes to medication or supplement regimens.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/FISH
[2] Medical News Today: https://www.medicalnewstoday.com/articles/fish-oil-vs-statins
[3] NPR: https://www.npr.org/sections/health-shots/2022/11/06/1134094540/statins-vs-supplements-new-study-finds-one-is-vastly-superior-to-cut-cholesterol