Based on the information available, there is no definitive evidence or warnings regarding negative interactions or side effects when taking Vascepa (icosapent ethyl) with probiotics. However, it is always recommended to consult with a healthcare professional or pharmacist before combining medications or supplements.

Vascepa is a prescription drug used to help reduce the risk of cardiovascular events, such as heart attacks and strokes, in adults with triglyceride levels above 150 mg/dL [1]. Probiotics, on the other hand, are live bacteria and yeasts that are beneficial for gut health, and they can be found in certain foods or taken as dietary supplements [2].

In a comprehensive database of drug-drug interactions, drugpatentwatch.com, there is no specific information or warnings regarding the combination of Vascepa and probiotics [3]. However, it is important to note that drug interactions can still occur even if they are not listed in databases or warnings.

In summary, while there is no evidence of negative side effects when taking Vascepa with probiotics, it is always best to consult with a healthcare professional before combining medications or supplements.

Sources:
[1] Vascepa (icosapent ethyl) [Prescribing Information]. Amarin Pharma, Inc.; 2021. Available from: <https://www.vascepa.com/sites/default/files/Vascepa-PI-2021-03-22.pdf>
[2] Probiotics. Mayo Clinic. Available from: <https://www.mayoclinic.org/healthy-lifestyle/consumer-health/multimedia/probiotics/sls-20076580>
[3] DrugPatentWatch.com. Available from: <https://www.drugpatentwatch.com/>