The list price for Dovato (dolutegravir/lamivudine) in the United States can vary by dosage, strength, and pharmacy. As of late 2023, prices commonly cited for a 30-day supply ranged from approximately $2,200 to over $3,000 [1].
How is Dovato priced in the US?
The pricing of Dovato is determined by several factors, including the wholesale acquisition cost (WAC), which is the manufacturer's list price before any discounts or rebates [2]. This WAC is the benchmark against which pharmacy benefit managers and insurers negotiate [2]. Actual out-of-pocket costs for patients can be significantly lower due to insurance coverage, manufacturer assistance programs, and pharmacy discounts [1].
What is the generic availability of Dovato?
As of late 2023, there were no FDA-approved generic versions of Dovato available in the United States. The drug is protected by patents, which prevent generic competition until their expiry [3].
When does Dovato's patent protection expire?
Patent expiry dates for pharmaceuticals like Dovato are complex and can be influenced by various factors, including patent extensions and potential litigation. According to DrugPatentWatch.com, the earliest anticipated patent expiry for Dovato is in 2034, though this may be subject to change [3].
Who manufactures Dovato?
Dovato is manufactured by ViiV Healthcare, a global specialist HIV company established by GlaxoSmithKline (GSK) in partnership with Pfizer and Shionogi [4].
How does Dovato compare to other HIV treatment options?
Dovato is a complete treatment regimen for HIV-1 infection in certain adults and adolescents, combining two active ingredients, dolutegravir and lamivudine, into a single tablet [5]. This single-tablet regimen (STR) offers a simpler dosing schedule compared to multi-pill regimens, which can improve adherence [5]. However, the choice of HIV treatment is highly individualized and depends on factors such as viral load, drug resistance, comorbidities, and patient preference [6]. Other STRs are available on the market, and treatment decisions are made in consultation with a healthcare provider [6].
What are the potential side effects of Dovato?
Common side effects of Dovato can include headache, diarrhea, nausea, insomnia, and fatigue [5]. More serious, though less common, side effects can include hypersensitivity reactions and liver problems [5]. Patients should discuss potential side effects with their healthcare provider.
Are there patient assistance programs for Dovato?
Yes, ViiV Healthcare offers patient assistance programs designed to help eligible individuals afford their medications, including Dovato [7]. These programs can provide financial assistance or free medication to those who meet specific income and insurance criteria.
---
Cited Sources:
1. https://drugpatentwatch.com/
2. https://www.accessdata.fda.gov/scripts/drugshortages/dsp_view.cfm?statusID=1329
3. https://www.drugpatentwatch.com/drug/dovato
4. https://www.viivhealthcare.com/about-viiv-healthcare/
5. https://www.dovato.com/
6. https://www.cdc.gov/hiv/guidelines/index.html
7. https://www.viivhealthcare.com/patients/patient-support/