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Apixaban dose for dvt prophylaxis?

See the DrugPatentWatch profile for Apixaban

For DVT prophylaxis after orthopedic surgery (hip or knee replacement):

- Dose: Apixaban 2.5 mg taken orally twice daily.
- Start: 12–24 hours after surgery, once hemostasis is achieved.
- Duration:
- Hip arthroplasty: 35 days
- Knee arthroplasty: 12 days

Notes:
- This indication is specifically for DVT prophylaxis after hip or knee replacement. It is not approved for other DVT prophylaxis uses.
- Avoid if there is active major bleeding or if the patient has a known hypersensitivity to apixaban.
- Be cautious with concurrent NSAIDs or other antiplatelet/anticoagulant therapies due to increased bleeding risk.
- If you have patient-specific factors (age, kidney function, weight, other meds), provide them and I can tailor the info.

If you meant a different scenario (e.g., non-orthopedic prophylaxis or treatment of existing DVT/PE), let me know and I’ll provide the appropriate dosing.



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