Diclofenac sodium 75mg how long to work?

It depends on the exact tablet type:

- Immediate-release diclofenac (usual oral 75 mg dose in some products): you often feel pain relief within about 30 minutes to 1 hour.
- Sustained-release diclofenac sodium 75 mg (SR form): onset is a bit slower, usually within 1–2 hours, and the full anti-inflammatory effect builds with regular dosing over a few days.

If you’re treating a chronic condition, the full anti-inflammatory benefit may take several days of continued use.

Tips:
- Take with food to reduce stomach upset.
- Swallow the tablet whole (especially if it’s sustained-release); don’t chew.
- Do not exceed the prescribed dose.

If you don’t notice any improvement after 2–3 days, or you have side effects (stomach pain, vomiting blood, black stools, severe dizziness, chest pain, swelling), contact your doctor promptly.

If you can share whether yours is immediate-release or sustained-release and what condition you’re treating, I can tailor the info more precisely.